TRAC 40: Protein Bioinformatics

The logical next step after genome sequencing or proteomics
analyses--and a necessary prequel to biomarker and drug target
discovery--is to identify proteins of interest and their activities.
This three-day course will combine lectures with computer labs to
provide an introduction to the bioinformatics resources and
methodologies commonly used for protein analyses. Course participants
are expected to know the basic biology of proteins, and will leave with
the ability to perform detailed analyses of protein sequences and
structures.

Topics:  Database Resources & Text Searching: where and how to look;
Theory and Application of Sequence Searches: BLAST, multiple sequence
alignment, and peptide/pattern match; Protein Classification: background
and how to construct protein families; Structure-based Analyses:
principles and tools, and how to do structure alignments and predict
functional sites; Protein Function Prediction: tour of how to do it and
how to avoid pitfalls; Biomedical Ontologies: introduction and uses;
Functional Interpretation of High-throughput Data: function and pathway.


Space will be limited to 24 participants

9:00 - 5:00 p.m.