TRAC 4: Cellular Immunology: Principles and Methods
Course emphasis is placed on understanding the immune system principles and the core immunology research methods. Particular focus will be placed on the cellular elements and their roles in the orchestration of the immune response. Because this field is contributing to novel therapies and is in a high state of flux, due attention will be given to new directions.
Topics:Cells of the adaptive immune system and of the innate immune system; special focus on B lymphocytes and T lymphocytes; Interactions between antibodies and antigens; Genes encoding antibodies; Immunological memory and the mechanisms involved in recall responses; The Major Histocompatibility complex (MHC) and how it controls adaptive immune response; Immunological tolerance and how the immune system is kept under control; Immunotherapy; How to generate and produce monoclonal antibodies; Using a flow cytometer for the analysis of cells of the immune system; Immunological assays (T cell proliferation, cytotoxic T lymphocyte cell assays, Western Blotting/Immunostaining, ELISA); The Mucosal Immune System
Related Bio-Trac Course: Bio-Trac 8: Immunochemistry and Monoclonal Antibody Production